I have been taking 200mg Sertraline since 2014 which helped tremendously but I just felt something else was needed. I heard that a friend with similar OCD to me was prescribed Pregablin. I did some research before speaking to my GP who started me on 25mg twice daily and am now on 300mg once a day. I have found it very effective in conjunction with Sertraline. The best way I describe how the meds work for me is that the Sertraline helps remove the immediacy to respond to the OCD triggers (spikes) and the Pregablin helps keep the anxiety at a managable level during this time. Neither remove the obsessions or compulsions but combined help me to cope better.